The cannabis plant comprises more than 80 chemicals, known as cannabinoids. Cannabidiol is the second most common. Unlike the most common – delta-9 tetrahydrocannabinol (THC) – it does not get you high.
The abbreviation of CBD is used so often that the US company Christian Book Distributors, which was established in 1978 and purveys Bibles, toys, games, home-schooling materials, and church supplies, changed its own name as a result.
Being non-psychoactive makes CBD more attractive to people seeking medical relief without mind-altering effects. CBD is thought to benefit the treatment of a number of conditions, making it one of the key steps to wellbeing.
Bipolar disorder was formerly known as manic depression. The most famous ever sufferer was Carrie Fisher – Princess Leia in the Star Wars films; she wrote of it a great deal. Bipolar disorder means a person’s mood alternates between low depressive and high manic episodes. These changes can be extreme and unpredictable. Bipolar disorder affects around 2% of people, equally split between genders. Over 30% of people who suffer from it commit suicide.
There is no cure for bipolar disorder. The prescription drug most often employed is lithium, which gives one-third of people who have taken it for over ten years of renal failure. Might CBD be the answer?
One study conducted in Michigan in 2016 found cannabis to help with bipolar disorder. So did another in Israel in 2015. People who took cannabis rich in THC were more prone to a negative mood response than those whose cannabis was rich in CBD.
Psychosis is a clear break from reality in the shape of hallucinations, lack of motivation, and paranoia. THC makes it worse, but CBD makes it better.
Antipsychotic drugs have been used since the 1950s, usually with some effect but with none at all in the case of a third of people. They have drastic side effects.
Cannabidiol as an Adjunctive Therapy in Schizophrenia: a Multi-Centre Randomised Controlled Trial was a study by the Institute of Psychiatry, Psychology, and Neuroscience of King’s College London that appeared in the American Journal of Psychiatry in 2019. It looked at 88 people with psychosis who hailed from the United Kingdom, Poland, and Romania. They took 0.035 oz of either CBD or a placebo for six weeks, as well as their usual drugs. CBD improved people’s mental health, making them less psychotic. People who suffer from psychosis often avoid conventional drugs because of their major side effects, which include becoming overweight, dizziness, drowsiness, and seizures. This is another reason to buy CBD oil.
The US National Cancer Institute admits that CBD relieves the symptoms of cancer. This happens because CBD reduces the ability of some kinds of tumor cells to reproduce.
It has been known for about 150 years that cannabis was a good way to deal with epilepsy. Neurologist Orrin Devinsky of New York University’s Langone Medical Center led the largest ever study into the relationship between the two in 2015. In the study, 162 epileptic people took an extract that was 99% CBD for 12 weeks. Seizures fell by a median of 36.5%. This is about as much as with regular drugs, but these are the most expensive.
Carpal Tunnel Syndrome
Carpal tunnel syndrome brings a burning sensation, numbness, and tingling or weakness in the hand. It is the product of pressure on the median nerve that lies in the carpal tunnel, which goes from the wrist to the hand. This nerve controls movement and feeling in the thumbs.
Carpal tunnel syndrome often results from repetitive motions of the wrist. Typing, pregnancy or conditions that include arthritis, diabetes, hypothyroidism, and obesity can all cause it. It might lead to people dropping things or having trouble sleeping, which leaves them moody and prone to poor decision-making. Some sufferers have declared that they felt like cutting their hands off.
If someone has carpal tunnel syndrome, the median nerve is inflamed. CBD’s anti-inflammatory effects have been mentioned here a number of times. Studies of animals have supported this. One, by Japan’s Tongji University in 2013, looked at pancreatitis. Another by Brazil’s University of Sao Paulo in 2012 concentrated on acute lung injury. There have been others.
Dr. Timna Naftali of Israel’s Kupat Holim Clinic explained that Crohn’s disease is an inflammatory bowel disease characterized by inflammation. It can affect any part of the gastrointestinal tract but most commonly occurs in the small intestine. Its primary symptoms are abdominal pain, bloody diarrhea, fever, and rectal bleeding.
Dr. Naftali led a randomized and placebo-controlled study into Crohn’s disease whose subjects were 46 people with moderately severe Crohn’s disease. They took cannabis oil that was 15% CBD and 4% THC. After eight weeks, over half these people experienced clinical remission. This research was featured at the United European Gastroenterology conference in 2018. Dr. Naftali recognized that 46 was not a huge number: “moving forward, larger and longer studies are required.”
Obsessive-compulsive disorder (OCD) strikes 2.3% of folk in the United States, more than is the case for bipolar disorder or schizophrenia. Sufferers are more likely to commit suicide. About half of the people afflicted by it get no benefit from traditional treatment.
Most often, OCD manifests itself in the need for order and fear of germs. As a consequence, people wash their hands incessantly, repeat words or phrases, rearrange or hoard things, or perform tasks in a particular order or a particular number of times.
A number of experiments have demonstrated CBD benefits in the face of OCD. One happened at the University of Sao Paulo School of Medicine in Brazil in 2014 and featured in the journal Fundamental Clinical Pharmacology. In it, rats in a sand-filled cage received the drug metaclor phenylpiperazine, which prompts OCD and is present in the recreational drug ecstasy. There were dozens of marbles in the cage; OCD-affected rats would bury them. Even when the dose of CBD was very low, no marbles got buried.